I love Linger also Snooze for brunch downtown. Linger has terrific food and used to be a mortuary! It has great cocktails for parents
I always enjoy Jagged Mountain Brewery and the Wynkoop Brewery. If you don't mind a short drive to food: Denver Biscuit Company. OMG. So decadent yet so amazing. It's the most American place I've ever eaten at.
The downtown has a lot of big box hotels for the most part - they will all be similar and around $200+ US per night. You might want to check out the Oxford? Otherwise, it's pretty much Marriott, Hyatt, Hilton etc
Our kids always love The Tattered Cover (
http://www.tatteredcover.com/) on the 16th Street Mall, and the Denver Museum of Nature and Science (
http://www.dmns.org/) is great for all ages. Oh and don't forget to hit up the massive REI downtown across the Platte.