I have pretty severe knee arthritis due to a very unusual fungal infection that likely occurred during ACL and meniscus repair that were torn while skiing in 2010. After 2 additional arthroscopies and 2 years after the initial surgery the fungus was diagnosed. I had a 4th knee surgery in the span of 3 years to scrape out all the infected bone and remove infected soft tissue including cartilage. The fungus destroyed just about all my meniscus and most of the cartilage. Almost exactly a year ago I had a autologous stem cell injection w/ PRP into my knee. It felt a little better for the 1st couple of months. I had post-procedure MRIs done at 3 and 6 months without any additional cartilage growth. Skied about 25 days last season and knee was pretty sore most of the season, maybe a little worse than the season before the procedure. Today, the knee feels a little worse than pre-stem cell. One my practice partners has a patient that had a shoulder stem cell injection who showed cartilage grown on a post-procedure MRI. Not sure how much and how many months post-procedure though. I’ve had patients who have had stem cell injection who have had improvement in pain and others who have not. Seems like a bit of a crap shoot overall.